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Their conclusion was that the value of steroids for idiopathic SSNHL remains unclear and the results of the randomized trials were contradictory

Wei, Z., Li, X., Li, X., Liu, Q

Koh A, Molinaro A, Sthlman M, et al

Mice in the Con group were fed a normal chow diet while those in the DM group were fed a high-fat diet (HFD, 60% kcal from fat, 20% kcal from protein, and 20% kcal from carbohydrate, Research Diets, NK) for 4 weeks to induce insulin resistance before being intraperitoneally injected with 40 mg/kg/day streptozotocin (STZ, Yuanye, China) for 3 days to induce partial insulin deficiency and hyperglycemia, mice with FBG 11.1 mmol/L were considered to be a successful model of diabetes

Author Contributions Authors equally contributed to research and preparation of the manuscript

doi: 10.1371/journal.pone.0025257 14 KepplerF.HamiltonJ