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For example, a study showed that 53% of 60 ME/CFS patients were tested for autoantibody against neurotransmitter receptor, muscarinic cholinergic receptor 1 and that these positive patients had a higher mean score of muscle weakness, painful node and forgetfulness as compared to healthy control [96]

Symptoms related to the digestive system include inflammation of the mouth and tongue ("bright red tongue"), vomiting, constipation, abdominal pain, and ultimately, diarrhea

Most core ingredients are safe at the doses used, methylfolate, vitamin D, iodine, choline, zinc at standard doses, omega-3

Conclusion Emerging evidence highlights the complex, multifactorial interplay between TMAO production, microbiome composition (both oral and gut), and miRNA regulatory networks in the pathogenesis of cardiovascular disease

F.RicaurteG

Clinical Phytoscience, 4 (1), 1-8