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PMID: 11705097

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In contrast to a purely descriptive approach, this review strives to synthesize these elements to illustrate the ongoing transition from broad neuroprotection towards a dual strategy of precision medicine for defined subgroups and mechanism-based combination therapies for a broader patient population

The disease burden of psoriasis can vary according to factors including anatomical location of plaques (e.g., face, scalp, genitals, hands, feet, and intertriginous areas), severity of symptoms such as itch and pain, impact on quality of life, treatment history, ethnicity, and other demographic characteristics [2,3,4,5,6,7]

Functional testing is currently not available through the NHS and is highly specialised

Drug seeking becomes compulsive after prolonged cocaine self-administration