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SLC7A5-mediated import of large neutral amino acids is essential for robust Th17 differentiation, as it facilitates the mTORC1 activation required for Th17 effector programming and inflammatory output

10.1002/bcp.70027 92 WedzichaJ

Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content

iScience 26 , 108393 (2023)

This is especially important for patients with diagnosed deficiencies, pernicious anemia, or for those who have undergone bariatric surgery

Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis