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Mechanistic studies reveal that inflamed intestinal tissues in IBD patients and corresponding animal models display characteristic ferroptosis features, including GSH depletion, suppression of GPX4 activity, and abnormal iron deposition

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This review is primarily concerned with discussing the recent understanding of redox signaling and gene regulation, the role of oxygenation in determining cell fate (apoptosis) and the downstream, protracted inflammatory state

(1988) Substrate specificity of rat liver glutathione 5-transferase isoenzymes for a series of glutathione analogues, modified at the -glutamyl moiety, Biochem

Uttamsingh V, Keller DA, Anders MW