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doi: 10.1017/s0033291700005134

However, results showed only a modest decline in hazard ratios across relatives of increasing affinity

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IL-8 is a cytokine that is involved in neutrophil recruitment/migration into the lungs and interleukin secretion was significantly greater after LC than Kentucky cigarette exposure, suggesting that in addition to being more toxic, that LCs may also induce more inflammation and place LC smokers at greater risk from chronic neutrophilia 17,27