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Toyoda, Y., Takada, T

doi: 10.1002/alz.12328

Cancer Immunol Res 4(10):820-822, 2016

Dissociated TXNIP combines with and activates the NLRP3 inflammasome to induce IL-1 expression in a NLRP3-ASC-caspase-1-dependent manner, thus causing inflammatory reactions