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In addition, a neuron-specific isoform of LSD1, known as LSD1n, has FAD-dependent H4K20me1/2 demethylase activity, which is enhanced by its interaction with the COREST complex 153

[83] assayed blood Glu and Gln in patients with recent onset and chronic schizophrenia to find that blood Gln/Glu ratio was increased with recent onset, versus decreased with long-standing disease