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While glyoxalase II substrate S-D-lactoylglutathione (SLG) acts as a precursor of the D-lactyl moiety for non-enzymatic D-lactylation, highlighting the multifaceted characteristics of lactylation as a biological regulatory system consisting of substrate specificity, lactate source, and enzyme dependence

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After anaesthetizing the SD rats with an intraperitoneal injection of pentobarbital (50 mg/kg), a thoracotomy was performed at the left 3-4 intercostal space to expose the heart

doi: 10.1111/nan.12405

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& Kurtenbach, R