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Simulation experiments have shown that the probability-based sampling design would help strengthen the FDAs compliance and enforcement programme, save money and resources by increasing inspection efficiency, and emphasise inspections in areas where they are needed most to reduce health disparities.9 According to recent studies of FDA inspections, retail violations for sales to minors were more likely to occur in neighbourhoods of lower socioeconomic status (SES) with a higher percentage of minority residents and weaker tobacco control policies.11 However, these findings, based on association studies, could lead to inspections targeting neighbourhoods with specific profiles (such as a high prevalence of African Americans) instead of identifying areas with an increased likelihood of underage sales violation

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SERT: serotonin transporter