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Briefly, using an AGI-30 impinger (Ace Glass Inc., Vineland, NJ, USA), 3R4F reference cigarettes (Tobacco-Health Research Institute, University of Kentucky, Lexington, KY) connected to a 60 mL syringe by a 3-way stopcock were smoked by suction in 20 mL of 1X phosphate buffered saline (PBS) 14

But there are large public health concerns if the introduction of e-cigarettes is leading more young people to become addicted to nicotine

Psychopharmacology (2013) 229:3140

In addition cable attenuation is also a problem lots of pedals use lots of interconnects

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In contrast to cigarettes, which produce smoke by burning tobacco, in other hand the e-cigarettes heat liquid to create an aerosol