Globally available over-the-counter 9 Included in: WHO policy recommendation and Model List of Essential Medicine since 2009 30-32 European Network for Smoking and Tobacco Prevention (ENSP) Tobacco Dependence Treatment Guidelines 33 NRT Combination Therapy is recommended by NICE as a first-line treatment option8 NRT single therapy is recommended by NICE as a second-line treatment option 8 Cytisine: Suitable for 18+18 Included in: World Health Organizations Policy Recommendation and Model List of Essential Medicines 2024 30.31 ENSP Tobacco Dependence Treatment Guidelines 33 Under consultation to add as first line treatment option 8 Varenicline: Suitable for 18+ 19 Included in: World Health Organizations Policy Recommendation and Model List of Essential Medicines 2021 30.31 ENSP Tobacco Dependence Treatment Guidelines 33 Varenicline is recommended by NICE as a first-line treatment option 8 Bupropion: Suitable for 18+20 Included in: World Health Organizations Policy Recommendation and Model List of Essential Medicines 2021 30.31 ENSP Tobacco Dependence Treatment Guidelines 33 Bupropion is recommended by NICE as a second-line treatment option 8 To keep in mind: NRT Combination Therapy is one of the most effective ways to help your patient quit for good 8 Speed of action and cravings relief Observational field studies indicate that cue-induced cravings are substantially responsible for relapse to smoking 35

Yet, an increase in cigarette prices may have a silver lining for domestic producers
IQOS has already achieved significant market penetration in countries like Japan and Italy, and PMI continues to expand its product line with new innovations
Big Tobacco 2.0: IQOS and a new industry strategy IQOS is part of a larger tobacco industry strategy to overhaul its reputation with novel products and electronic devices, including heated tobacco products and e-cigarettes
This offers a smoother, more controlled vaping experience
By reducing air pollution levels , authorities can diminish the risk of various diseases such as lung cancer, heart disease, stroke, asthma and respiratory diseases