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A prospective therapeutic drug monitoring study showed that steady-state plasma olanzapine concentration/dose ratio closely correlated with CYP1A2 metabolic activity, and described a statistically significant five-fold lower dose-corrected steady-state plasma olanzapine concentration in smokers [21]

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One of the refrains we hear from kids who do this kind of work is, when they get the tobacco sickness, they say, I felt like I was going to die,' said Reid Maki, Director of Social Responsibility and Fair Labor Standards Coordinator, Child Labor Coalition for National Consumers League

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