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Results The effect of dietary L-carnitine supplementation on the carnitine concentration, carnitine synthesis gene expression and triglyceride levels in tissues During the experiment, the fish were in good health and showed no growth differences compared with control fish (data not shown)

However, the physiological substrates of OCTN1 are still matter of discussion (Pochini et al., 2019 and Table 1)

Among cases of severe hepatotoxicity occurring during VPA therapy, survival has been reported mainly in those patients treated with carnitine [6467], and this approach is likely to be biased