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The fluorescence quenching data were analyzed using the SternVolmer equation: where F 0 and F represent the fluorescence intensities in the absence and presence of the quencher respectively, [ X ] is the molar concentration of the quencher and K sv is the SternVolmer constant obtained from the slope of the plot

All current evidence is from animal or in vitro models

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The REDEFINE trials reported gastrointestinal adverse events in 79.6% of CagriSema patients compared to 39.9% in placebo groups

& Foley, J