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Because ZYN contains no tobacco leaf, it may reduce exposure to certain tobacco-specific compounds found in snus, including TSNAs and polycyclic aromatic hydrocarbons

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A significant difference was not observed when comparing past smokers with never-smokers (HR = 1.1

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age of onset of vaping, cigarette smoking, psychological distress) and information on motivation leading up to onset (and discontinuation) of vaping, would have provided additional context regarding the role of vaping in daily cigarette consumption

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