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Although in the past many believed, that tobacco prevents illnesses and cures various conditions, chemists who extracted pure nicotine found it as poison

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Beyond the substance itself, individual factors include genetic predisposition (approximately 40 to 60 percent of addiction risk is heritable), age of first use (earlier onset dramatically increases risk), co-occurring mental health conditions, history of trauma, and the social and environmental context of use

Over the past decade, they have reported that even just one minute of exposure to secondhand smoke from marijuana reduces blood vessel function in rats similarly to the effects of secondhand smoke from tobacco, and rats exposed to smoke from marijuana or tobacco once a day for eight weeks have similar harmful effects in their hearts