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Additionally, it promotes stem cell activity, supports bone repair, and has shown neuroprotective benefits against age-related cognitive decline in animal models 1,3

Clinical evidence remains limited

This nonapeptide, first isolated from the cerebral venous blood of rabbits during sleep, has been shown to induce slow-wave sleep, modulate pain perception, and exhibit potential antioxidant and immunomodulatory properties

Copper peptides can complement this effect by strengthening the skins structure, which helps lines look softer because the skin has better support beneath the surface

Tirzepatide remains the most effective FDA-approved option

The CIR (Cosmetic Ingredient Review) has concluded this ingredient to be safe as used in cosmetics and it has not shown to be a skin sensitizer in testing (unless you have a known rice allergy)