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The FDA proposed the rule in April 2022 but missed the self-imposed deadline to finalize it in August

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Cancer Res 48:69126917 Prokopczyk B, Hoffmann D, Bologna M, Cunningham AJ, Trushin N, Akerkar S, Boyiri T, Amin S, Desai D, Colosimo S, Pittman B, Leder G, Ramadani M, Henne-Bruns D, Beger HG, El Bayoumy K (2002) Identification of tobacco-derived compounds in human pancreatic juice

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I would have thought that was grounds for considerable puzzlement, even to Your Lordship