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To assess copper-dependent regulation of autophagy-related genes, the expression of six genes ( HSP90AA1 , GABARALP1 , UBC , PRAGC , PLOD2 , LAMTOR3 ) was measured in HepG2 and HepG2 ATP7B-KO cells after CuCl treatment

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It will resort to alternative survival-dependent problem solving

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Overall, these neuropathology observations suggest that GHK-Cu acts on molecular markers associated with different pathways in the brain in a sex dependent manner, and that additional drugs could be added as a cocktail to be more effective in enhancing resilience to age-related cognitive decline