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It remained in this location for 25 years

While cigarette manufacturers' ads avoided the personal harm to come from smoking, Allstate insurance wasn't averse to using cigarettes as a tool of distracted driving in this 1940 advertisement, whose story tells of a driver rummaging in his pocket for a light only to run down a little girl

That tradition lives on here in the Ota district of Iwate-machi, Iwate Prefecture, an old tobacco-farming center in the Tohoku region

This tobacco standard reference material and others help inform the evaluation of data on harmful and potentially harmful constituents submitted by manufacturers and importers. NIST SRM 3222 is certified for amounts of nicotine, the primary cause of tobacco addiction, and two tobacco-specific nitrosamines: N-nitrosonornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

Included are PDF and Google Slides versions of the activity with answer key