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Tremors Weakness Stumbling and/or incoordination Depression Hyperactivity Lethargy (in high doses) Fast breathing or difficulty breathing Drooling Dilated pupils Vomiting Diarrhea Possible seizures Collapse Either bradycardia (slow heart rate), tachycardia (high heart rate) and/or cardiac arrhythmias Diagnosis Diagnosis of nicotine toxicity is generally based on a history of exposure to or eating of nicotine products and development of some of the toxic signs

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