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4 Antiviral effects of PYC PYC exhibits antiviral activity against a broad range of viruses, including hepatitis C virus (HCV), dengue virus (DENV), classical swine fever virus (CSFV), and human immunodeficiency virus (HIV), among others (Figure 1) ( Substantial insight into PYCs antiviral potential has emerged from in vitro and in vivo studies of HCV

613 In a phase 2 study, vixotrigine was investigated for the treatment of idiopathic or diabetes-associated painful SFN

CSD is closely associated with migraine aura but is also observed in cerebral ischemia, epilepsy, and traumatic brain injury (10)

Among the glycolytic enzymes found to be increasingly oxidized, TPI, PGM1, and GAPDH were observed in late AD patients, whereas increased FBA, Eno1, and PK oxidation were found in EAD and MCI subjects as well

Excessive autophagy also induces granulosa cells death (BioRender.com)

Both the application of antibiotic stewardship principles and timely considerations through the regulatory pathways are needed to release the next generation of antibiotics that are suitable for the fight against superbugs