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Smoking is harmful, as it causes combustion

To address these limitations, the objective of this study was to systematically evaluate the association between household SHS exposure and ADHD risk among US children

"Our analyses show that there is significant toxicity in harm reduction products, and reduction of carcinogens in harm reduction mainstream smoke does not necessarily reduce the toxicity of unfiltered sidestream smoke." Researchers developed tests with human embryonic stem cells, which are similar to young embryos, to compare the toxicity of mainstream (inhaled) smoke and sidestream smoke from both conventional and harm reduction cigarette brands

doi:10.1038/nrcardio.2013.8

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