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Tobacco and cannabis use in isolation have devastating consequences for people with psychosis, so we wanted to see if people who co-use cannabis and tobacco had more severe psychiatric symptoms and if they were at greater risk for developing psychosis in the first place. The study found that regular use of either cannabis or tobacco was linked to anxiety, depression and early psychotic experiences

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Collectively, these responses in transcriptional programming and cellular composition are consistent with smoke exposure pushing tuft-like cells toward incomplete or compromised ionocyte or PNEC phenotypes, further supporting our proposed rare cell lineage

I bumped into two girls about my age, who chatted me up and offered me a Marlboro Light

They can be used for loose tobacco or unopened cigarette packs