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In human colorectal cancer cell lines, loss of proapoptotic protein Bax led to 5-FU resistance ( 2.1.2 Ferroptosis Ferroptosis is an iron-dependent, non-apoptotic method of cell death, induced by reactive oxygen species and an imbalance of intracellular lipid redox

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doi: 10.1128/iai.69.6.4034-4040.2001 58 StoneKKBermudezEPryorWA

Epub 2022 Jul 5

All the components of this antioxidative defensive system act in collaboration to regulate the problems of uncontrolled oxidation and ultimately shield the plant cells from oxidant harm by scavenging these toxic ROS [11]