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Multiple cell types in the liver, including macrophages, neutrophils, other immune cell types and hepatocytes, are involved in fatty liver disease inflammation

It was first mapped via a genomic sequence database and then identified in the human pituitary gland ( As all GPR ligands are hydroxy-carboxylic acids, the GPRs are now HCA receptors (HCARs

Expression of AIM2 in rheumatoid arthritis and its role on fibroblast-like synoviocytes

FOXO1, a pro-apoptotic transcription factor in cartilage, was investigated and it was found that silencing of FOXO1 in chondrocytes resulted in a significant reduction in the mRNA levels of pro-apoptotic genes caspase-3, caspase-8, caspase-9 and TRAIL

Exposure of the liver to xenobiotic substances means the body prepares itself by increasing detoxification enzymes, i.e., cytochrome P-450 mixed-function oxidase

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