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Description

Protein molecule that contains a binding site for another specific molecule (called a ligand)

Progranulin (PGRN), which is a secreted protein encoded by GRN and produced by myeloid cells and neurons, plays an immunoregulatory role and contributes to the regulation of lysosomal function

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On the other hand, Gram-positive Lactobacilli and Bifidobacteria are considered to be anti-inflammatory bacteria (Sanders et al., 2021)

This is likely due to metabolic dysfunction-associated steatohepatitis-related aberrant T cell activation, which causes tissue damage and impairs immune surveillance 122