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When weight comes off quickly, there's less opportunity to preserve and rebuild muscle tissue

When to Adjust Dosing Increase dose if: After 4-6 weeks at current dose, no measurable body composition changes occur, youre tolerating current dose without side effects, youre below the upper clinical range (1 mg daily), and your physician approves escalation based on comprehensive assessment

Moludi J, Khedmatgozar H, Saiedi S, Razmi H, Alizadeh M, Ebrahimi B

Vitamin B12 also participates in increasing the activity of antioxidant enzymes, reducing DNA damage, reducing inflammatory cytokines, and eliminating free radicals (Tamura et al

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The answer depends on several factors, including the cause and severity of deficiency, your overall health, and how long symptoms have been present