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Storage Quick Reference Community sources commonly describe storing unopened vials frozen, with reconstitution limited to a 3-4 week supply

then they will be gently mixed by rolling the vial around slowly

Peter Marks, head of FDAs Center for Biologics Evaluation and Research, in a news release

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How vitamin B12 is absorbed and stored in the body B12 must be absorbed through food, is found exclusively in animal foods and is then transported into the bloodstream via a special transport route with the help of the so-called intrinsic factor