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Fill the Cone: Begin by gently packing the ground material into the cone

According to the CDC, tobacco users who dip or chew 8 to 10 times per day may be receiving the nicotine equivalent of 30 to 40 cigarettes per day

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We determined the appropriate functional form of CPD for cotinine-prediction by fractional polynomials including comparison of log-likelihoods [17] and applied it in subsequent analyses

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