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A: These cigarette sticks are made only with chocolate, so they might end up melting in the coffee as a result

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Otherwise, it can make its way inside through mechanical ventilation devices (like HVAC systems) and small openings or cracks that might be around closed windows

Yet, considering the importance of mitochondrial dysfunction in COPD and the increasing evidence highlighting mtDNA gene expression and methylation as potential biomarkers in a variety of diseases related to mitochondrial dysfunction and ageing, future studies may explore the impact of age and smoking status of COPD patients to provide a deeper understanding on mtDNA methylation and gene expression