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Description

Ratio of bcl-xshort to bcl-xlong is different in good- and poor-prognosis subsets of acute myeloid leukemia

The quality of the vials appeared to be substandard while the labels were dodgy

FINLEY et al

48 The human GSTP1 gene exists as two functionally different variants, with both variants having documented nucleotide transitions from isoleucine to valine at codon 105 (AG) and alanine to Val at 114 (CT)

In most healthy cells, this ratio is maintained in a highly reduced state between 30:1 and 100:1

However, compared with humans, the ratio of the oral dose to the serum concentration seems to be higher in rats than in humans, making it difficult to directly apply relevant studies to humans (Meftah et al., 2021)