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Whatever the goal, a structured and medically supervised approach is often the best place to start

doi: 10.3389/fimmu.2018.02134 Received 09 June 2018 Accepted 29 August 2018 Published 20 September 2018 Volume 9 - 2018 Edited by Fabio Malavasi, Universit degli Studi di Torino, Italy Reviewed by Benjamin Bonavida, University of California, Los Angeles, United States

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Consume excessive alcohol Have immune dysfunction Are older adults (see below for more on this) Have gastrointestinal disorders

This condition is concerning for both patients and healthcare providers