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INH is a prodrug that enters the Mtb cytoplasm via passive diffusion, where it inhibits mycolic acid synthesis by targeting the InhA enzyme, an essential catalyst in an early step of the mycolic acid biosynthetic pathway (Mitchison, 1956)

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For the category as a whole, that is likely a constructive signal

Fine particles (PM 2.5 ) pose the greatest health risk 6

1a, the odds of smoking increase slightly among those between 18 and ~ 27 years of age, but this association weakens for smokers above the age of ~ 27