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Reduction in efficacy may, unfortunately, lead to inappropriate adjustments of medications to higher dosages

However, lung cancer patients might have smoking and age-related comorbidities such as chronic obstructive pulmonary disease and interstitial lung diseases in which Pseudomonas aeruginosa is frequently present

In March 2025, brand ambassador John Heald received additional feedback calling for a major change to smoking policies onboard

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Cannabis use disorder Cannabis use disorder is characterized by symptoms such as intense cravings, an inability to stop/reduce use or continuing use despite negative consequences