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A recent global systematic review revealed substantial evidence that nicotine e-cigarettes can cause dependence or addiction in non-smokers, as well as solid evidence that young non-smokers who use e-cigarettes are more likely to start smoking and become regular tobacco users than non-users 14

The DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, 5th ed.) uses the term Cannabis Use Disorder with graded severity (mild, moderate, severe) rather than the binary dependence vs

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Leave your suggestions for an updated 21st century moniker in the comment section below

References 1) Kowalewska A, Mazur J, Dzielska A, Chechowska M