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For example, compounds isolated from crude extracts of Andrographis paniculata like, (8R12S)-Isoandrographolide, directly downregulate inflammasome-related proteins such as NLRP3, ASC, and caspase-1

Because we observed that a wide range of OXPHOS and glycolytic scores represent metabolic heterogeneity of single culturing wells, we separated low, mid and high HLA-DR and CD86 expressing cells and compared their metabolic and immune features between inflammatory and tolerogenic conditions

This de novo thymopoiesis is essential for building a diverse T-cell repertoire and achieving self-tolerance

Workers with prolonged exposure to 4-aminobiphenyl exhibit significantly higher bladder cancer rates compared to the general population (Tao et al., 2013

SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination

The durability advantage is also substantial