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However, mSOD1 induces morphological and functional activation of microglia and when motor neurons are co-cultured with microglia, extracellular mSOD1 injures motor neurons

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To counteract this, cells have evolved antioxidant systems such as superoxide dismutases (SODs), which convert O 2 into hydrogen peroxide (H 2 O 2 ) [2,5,6]

For a long time I used to think that it was possible to use a single proxy (such as telomere length) in order to measure biological aging