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They concluded that: Completely substituting e-cigs for combustible cigarettes reduces users exposure to numerous toxicants and carcinogens present in cigarettes, and that completely switching from regular use of combustible cigarettes to e-cigs results in reduced short-term adverse health outcomes. Shouldnt nicotine-addicted smokers have the choice to be able to reduce their toxic exposures and health risks by switching to a much less harmful nicotine product

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Eastern Europe and Central Europe also showed reductions in their burden: Eastern Europe fell from 250,156 (95% UI: 236,016264,173) in 1990 to 139,249 (95% UI: 120,265157,679) in 2021, and Central Europe dropped from 139,647 (95% UI: 130,170149,362) in 1990 to 109,911 (95% UI: 97,442121,846) in 2021(Table 1, Supplementary Table S2)