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Liver tissue and serum samples were collected at multiple time points for histological evaluation (HE staining), apoptosis detection (TUNEL staining), proliferation assessment (Ki67 immunohistochemical staining), and measurements of liver transaminase (ALT, AST), inflammatory markers (IL-1, IL-6, TNF-), and oxidative stress indicators (SOD, MDA, GSH)

DOI:10.1007/s11886-017-0909-z 11

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In order to compensate for the high levels of oxidative stress in cells, endogenous antioxidant enzymes are necessary to maintain redox balance [48]

Statements Author contributions CL, CM, TT, and RK conceived the review and led the project administration