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359 This reduction in ROS can inhibit autophagy in IVDs and reduce the apoptosis of myeloid cells caused by oxidative stress, maintaining the stability of the structure of IVD

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Cells with increased mitochondrial activity were more resistant to 5FU treatment in the acute setting (72 h), as shown in a dose-dependent manner (Fig

Trospium (1530 mg b.i.d.), which does not cross the bloodbrain barrier, as well as solifenacin (5 mg o.i.d), and darifenacin (7.515 mg o.i.d.), that selectively stimulate peripheral M3 muscarinic receptors, are less likely to cause cognitive side effects and may be therefore preferred [114, 232]