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Peptide degradation accelerates after 28 days even under proper refrigeration at 28C, resulting in progressive loss of bioactivity due to oxidation and hydrolysis of peptide bonds

Han L, Rowinsky E, Brooks C, Zal T, Zal MA, Burks J, Zhou J, Ciurea SO, Alatrash G, Cortes J, Kantarjian HM, Andreeff M , Ravandi F, Konopleva M

Lacbay CM, Waller DD, Park J, et al

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Rapid reversed-phase high-performance liquid chromatography method for the quantitation of vicine, convicine and related compounds

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