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The fact that the additives lead to more TPM is, itself, an important indicator of increased toxicity because the TPM in cigarette smoke leads to substantial increases in risk of cardiovascular disease, with a steep and highly nonlinear dose-response at low levels of exposure [123][126]

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The more and longer you smoke, the higher your risk of bladder cancer

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19.Marry before you have settled habits or it will be difficult to make the mutual concessions that marriage entails