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Future research priorities should include: (1) randomized controlled trials with standardized dietary interventions and well-defined stroke subtypes, (2) identification of predictive biomarkers for dietary treatment response, (3) investigation of optimal intervention timing and duration, (4) evaluation of combined dietary and pharmacological approaches, and (5) development of personalized nutrition strategies based on genetic, metabolomic, and microbiome profiles

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249,445,446,447,448,449 Uric acid exerts multifaceted effects on endothelial function and vascular health through its interactions with NO, ROS, and inflammatory pathways, highlighting its potential role in the pathogenesis of cardiovascular diseases like atherosclerosis

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In contrast, CPI plants showed increased CAT activity, potentially facilitating CPSMV infection