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The modified IBB scale for assessment of forelimb function impairment (see 66, 67)

The withdrawals/removals included: Placebo Group (11 withdrawals, including 5 due to adverse effects) 4 participants withdrew because their parents lost interest in the study 1 child was removed by the PI due to a change of school 1 participant began behavior medication 1 week into study and was removed by the PI 3 cases of loose stools/ diarrhea (all 3 had gut issues prior to starting, and the continuation of those symptoms caused them to drop out) 1 participant had increased stimming (rubbing face) - history of this, but seemed to worsen 1 participant withdrew due to behavior problems Treatment Group (8 withdrawals, including 3 due to adverse effects) 2 participants were removed from the study because they made changes in their psychiatric medications in the first few weeks of the study

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(2022, June 16)

Similarly, patients with more than two lesions were excluded by 64% of trials, and patients with signs of joint-wide OA were excluded by 79% of trials