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HHcy can also contribute to neuronal toxicity through excitotoxic mechanisms [68] primarily by overstimulating N-methyl-D-aspartate (NMDA)-type glutamate receptors

doi: 10.1097/00000542-199612000-00028

Gastroenterology 156(2):477-491 e471

Romero-Figueroa MDS, Ramrez-Durn N, Montiel-Jarqun AJ, Horta-Baas G

doi: 10.3389/fncel.2025.1588645 Received 06 March 2025 Accepted 14 April 2025 Published 20 May 2025 Volume 19 - 2025 Edited by Neville Ng, University of Wollongong, Australia Reviewed by Mingzi Zhang, University of Southern California, United States Slawomir Jakiela, Warsaw University of Life Sciences, Poland Vasileios Balis, Aegean College, Greece Updates Copyright 2025 Liu, Sun, Guo, Yuan, Zhu, Lu, Chen, Qu, Feng and Yang

In addition, studies suggest roles in angiogenesis, peripheral nerve outgrowth, antioxidant defense, and modulation of inflammatory activity, including in models of chronic pulmonary injury[2]