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In an OIS model induced by Nras G12v overexpression in hepatocytes of immunodeficient Nod Scid Gamma (NSG) mice, senescent cells were successfully eliminated when treated with the anti-uPAR CAR-T cells

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The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells

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Protein concentrations were determined by the Bradford assay and equivalent amounts (1015 g) of total cellular proteins were separated by electrophoresis on a 12% SDS - polyacrylamide gel