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Description

Masse, W

When MDA5 detects viral dsRNA, the CARD domains undergo ISG15-mediated ISGylation, facilitating MDA5 oligomerization onto the RNA and subsequent CARD clustering and binding to MAVS (99, 104)

Previous studies have suggested that cysteine availability is a major determining factor for the partitioning of cysteine sulfur to either GSH, taurine, or inorganic sulfates in rat liver (29,30)