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Taking enzyme-responsive nanomaterials as an example, there are notable physiological and tumor microenvironment differences between animal models and human models in preclinical biosafety evaluations, complicating their clinical translation (Cao et al., 2019)

Western blotting Total cellular proteins were extracted from cultured cells using RIPA Buffer (Biosolution, Korea) supplemented with protease inhibitor Cocktail (Roche, Germany)

NSAIDs may counteract some of BPC-157s gastroprotective effects

As the medium already contains 200 M methionine and 400 M serine, the relative proportion of the labelled species is 50 and 33%, respectively

Ifngamma-mediated repression of system xc(-) drives vulnerability to induced ferroptosis in hepatocellular carcinoma cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Ookhtens M., Lyon I., Fernndez-Checa J.C., Kaplowitz N